Telmisartan Tablets USP 80mg

Mechanism of Action

Telmisartan is an angiotensin-II receptor antagonist with antihypertensive activity due mainly to selective blockade of angiotensin-II receptors and the consequent reduced pressor effect of angiotensin II.


Telmisartan is rapidly absorbed from the gastrointestinal tract; the absolute oral bioavailability is dose dependent and is about 42% after a 40 mg dose and 58% after a 160-mg dose. Peak plasma concentrations of telmisartan are reached about 0.5 to 1 hour after an oral dose. Telmisartan is over 99% bound to plasma proteins. It is excreted almost entirely in the faeces via bile, mainly as unchanged drug. The terminal elimination half-life of telmisartan is about 24 hours.


  • It is indicated for the treatment of hypertension.
  • It is indicated in the treatment of heart failure
  • It is indicated for prevention of cardiovascular events in patients with established atherosclerotic cardiovascular disease, or type 2 diabetes mellitus with target-organ damage.

Side Effects

Side effects are usually mild. Symptomatic hypotension including dizziness may occur, particularly in patients with intravascular volume depletion. Hyperkalemia occurs occasionally;

Dosage and Administration

Telmisartan is administered orally.

Hypertension: usually 40mg once daily (but 20mg may be sufficient), increased if necessary after at least 4 weeks, to max 80mg once daily

Prevention of cardiovascular events, 80mg once daily

Hepatic impairment

20-40 mg once daily in mild or moderate impairment; avoid in severe impairment or biliary obstruction.

Renal impairment

20mg mg once daily in severe impairment


Store below 30C in a dry place. Protect from light. Keep medicine out of reach of children.


3 × 10 Alu-Alu Blister